魏琳，女，于2013年6月，在湖南大学分析化学专业获博士学位，师从国际著名分析化学家Edward S. Yeung教授。在此期间，作为主要研究成员参与完成“实时单分子光谱分析及其在功能纳米材料研究中的应用”、“功能化金纳米颗粒的实时单分子光谱分析及其在生物医学研究中的应用”、“基于实时单分子光谱技术的纳米颗粒早期自组装过程研究”等多项自然科学基金课题，并于2010-2012年在美国Iowa State University和能源部下属Ames实验室访问研究两年。2013年10月，受聘于湖南师范大学，在2015年破格晋至副教授职称。获得国家自然科学基金委青年基金项目一项，湖南省教育厅优秀青年基金项目一项。长期从事贵金属纳米材料的制备和修饰，光学显微成像方法的开发与应用工作。相关研究成果均发表在Anal.Chem., Nanoscale, ACS Appl. Mater. Interfaces, J. Phys. Chem. B, Talanta等国际著名杂志上。
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发表的论文列表： 28. D. Zhang, Z. Ye,L. Wei*, H. Luo* and L. Xiao*. Cell Membrane-Coated Porphyrin Metal-Organic Frameworks for Cancer Cell Targeting and O2-Evolving Photodynamic Therapy.ACS Appl. Mater. Interfaces, 2019. 27. F. Wang, Y. Han, S. Wang, Z. Ye,L. Wei*and L. Xiao*. Single-Particle LRET Aptasensor for the Sensitive Detection of Aflatoxin B1 with Upconversion Nanoparticles.Anal. Chem., 2019, 91, 11856-11863. 26. F. Wang, Y. Li, Y. Han, Z. Ye,L. Wei*, H. Luo and L. Xiao*. Single-Particle Enzyme Activity Assay with Spectral-Resolved Dark-Field Optical Microscopy.Anal. Chem., 2019, 91 (9), 6329–6339. 25.Y. Chen, Y. Lian, M. Huang,L. Wei*and L. Xiao. Dual Mode Fluorometric/Colorimetric Sensor for Cu2+ Ions Detection based on Hybridized Carbon Dots and Gold-Silver Core Shell Nanoparticles.Analyst, 2019, 144, 4250-4257. 24. Z. Ye, R. Weng, Y. Ma, F. Wang, H. Liu,L. Wei*, and L. Xiao*. Label-Free, Single-Particle, Colorimetric Detection of Permanganate by GNPs@Ag Core–Shell Nanoparticles with Dark-Field Optical Microscopy. Anal. Chem., 2018, 90 (21), 13044–13050. 23. L.Wei,.; Zheng, X.; Ye, Z.; Xu, Y.; Zhang, D.; Xiao, L.* Positively Charged Small Size Fluorescent Conjugated Polymer Dots for Gene Delivery and Intracellular Imaging. Nanotheranostics,2018, 2, 157-167. 22.Z. Zhang, D. Zhang,L. Wei,X. Wang, Y. Xu, H. Li, M. Ma, B. Chen and L. Xiao*. Temperature responsive fluorescent polymer nanoparticles (TRFNPs) for cellular imaging and controlled releasing of drug to living cells.Colloids and Surfaces B: Biointerfaces, 2017, 159, 905-912. 21.L.Wei,Y. Ma, X. Shi, Y. Wang, X. Su, C. Yu, S. Xiang, L. Xiao* and B. Chen*. Living cell intracellular temperature imaging with biocompatible dye-conjugated carbon dots. J. Mater. Chem. B, 2017, 5, 3383-3390. 20.L. Wei,Y. Ma, X. Zhu, J. Xu, Y. Wang, H. Duan and L. Xiao*.Sub-diffraction-limit localization imaging of a plasmonic nanoparticle pair with wavelength-resolved dark-field microscopy.Nanoscale, 2017, 9, 8747-8755. 19.X. Su, Z. Li, X. Yan, L. Wang, X. Zhou,L. Wei, L. Xiao* and C. Yu*. Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay.Anal. Chem.,2017, 89(6), 3576-3582. 18.L. Wei,Z. Ye,Y. Xu,B. Chen,E. Yeung and L. Xiao*. Single Particle Tracking of Peptide-Modified Nanocargo on Lipid Membrane Reveals Bulk-Mediated Diffusion.Anal. Chem., 2016, 88(24), 11973-11977. 17.L. Wei,J. Xu, Z. Ye, X. Zhu, M. Zhong, W. Luo, B. Chen, H. Duan, Q. Liu and L. Xiao*,Orientational Imaging of a Single Gold Nanorod at the Liquid/Solid Interface with Polarized Evanescent Field Illumination. Anal. Chem., 2016, 88(4), 1995-1999. 16.Q.Yang, Z. Ye, M. Zhong, B. Chen, J. Chen, R. Zeng,L. Wei*,H. Li* andL. Xiao*, Self-assembled Fluorescent Bovine Serum Albumin Nanoprobes for Ratiometric pH Measurement inside Living Cells.ACS Appl. Mater. Interfaces, 2016, 8(15), 9629-9634. 15.Y. Ma, Z. Zhang, Y. Xu, M. Ma, B. Chen, L. Wei*and L. Xiao*. A Bright Carbon-dot-based Fluorescent Probe for Selective and Sensitive Detection of Mercury Ions.Talanta, 2016, 161, 476-481. 14.L. Wei, Z.Ye, W. Luo, and L. Xiao*,Photo-induced Redistribution of Single Molecules at the Solid/liquid Interface.Talanta,2016,155, 229-234. 13.Wenjuan Luo, Ming Wu, Shuang Li, Yueling Xu, Zhongju Ye, Lin Wei,Bo Chen, Qing-Hua Xu, and Lehui Xiao*, Nanoprecipitation of Fluorescent Conjugated Polymer onto the Surface of Plasmonic Nanoparticle for Fluorescence/Dark-Field DualModality Single Particle Imaging.Anal. Chem., 2016, 88(13), 6827-6835. 12.Chung-Yan Poon,Lin Wei, Yueling Xu, Bo Chen, Lehui Xiao,* and Hung-Wing Li*. Quantification of Cancer Biomarkers in Serum Using ScatteringBased Quantitative Single Particle Intensity Measurement with a Dark-Field Microscope.Anal. Chem., 2016, 88(17), 8849-8856. 11.H.Tan, W. Luo,L. Wei,B. Chen, W. Li, L. Xiao*, Z. Liu* and S. Liang,. J. Phy. Chem. B, 2016, 120(12), 3081-3088. 10.Q. Yang,L. Wei,X. Zheng and L. Xiao*. Single Particle Dynamic Imaging and Fe3+Sensing with Bright Carbon Dots Derived from Bovine Serum Albumin Proteins.Sci. Rep., 2015, 5, 17727. 9.L. Wei,P. Zhou, Q. Yang, Q. Yang, M. Ma, B. Chen and L. Xiao*. Fabrication of Bright and Small Size Semiconducting Polymer Nanoparticles for Cellular Labelling and Single Particle Tracking.Nanoscale, 2014, 6, 11351-11358. 8.L. Wei,Q. Yang, and L. Xiao*. Tempo-spatially Resolved Cellular Dynamics of Human Immunodeficiency Virus Transacting Activator of Transcription (Tat) Peptide-modified Nanocargos in Living Cells.Nanoscale, 2014, 6, 10207-10215. 7.L. Wei,X. Zhao, B. Chen, H. Li, L. Xiao* and E. S. Yeung*. Frozen Translational and Rotational Motion of Human Immunodeficiency Virus Transacting Activator of Transcription Peptide-Modified Nanocargo on Neutral Lipid Bilayer.Anal. Chem., 2013, 85, 5169–5175. 6.L. Wei,C. Liu, B. Chen, P. Zhou, H. Li, L. Xiao* and E. S. Yeung*. Probing Single-Molecule Fluorescence Spectral Modulation within Individual Hotspots with Subdiffraction-Limit Image Resolution.Anal. Chem., 2013, 85, 3789-3793. 5.L. Xiao,L. Wei,C. Liu, Y. He and E. S. Yeung*. Unsynchronized Translational and Rotational Diffusion of Nanocargo on a Living Cell Membrane.Angew. Chem. Int. Ed., 2012, 51, 4181-4184. 4.L. Xiao, J. W. Ha, G. Wang, L. Weiand N. Fang*. Determining the Full Three-Dimensional Orientation of Single Anisotropic Nanoparticles by Differential Interference Contrast Microscopy.Angew. Chem. Int. Ed., 2012, 51, 7734-7738. 3.L. Xiao,L. Wei,X. Cheng, Y. He* and E. S. Yeung. Noise-Free Dual-Wavelength Difference Imaging of Plasmonic Resonant Nanoparticles in Living Cells.Anal. Chem., 2011, 83, 7340-7347. 2.L. Wei,L. Xiao and Y. He*. Synthesis of water soluble silver-nanoparticle-embedded polymer nanofibers with poly(2-ethyl-2-oxazoline) by a straightforward polyol process.J. Mat. Res., 2011, 26, 1614-1620. 1.L. Xiao,L. Wei,Y. He* and E. S. Yeung. Single Molecule Biosensing Using Color Coded Plasmon Resonant Metal Nanoparticles. |
