基本信息
张友玉，博士，二级教授，博士生导师。主要从事化学生物学及纳米分析化学等领域的研究。主持国家自然科学基金面上项目6项，国家基金重点项目协作项目1项，省部级重点及一般项目10余项。以第一作者和通讯作者在Sci. Adv.,Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun.等国际著名刊物上发表高水平研究论文200余篇，获国家授权发明专利10余项。获湖南省自然科学奖二等奖1项，湖南省科学技术进步奖二等奖1项，中国分析测试学会科学技术奖（CAIA奖）二等奖1项。曾获湖南师范大学科研标兵和芙蓉百岗明星等称号。
主持课题（部分）
1.国家自然科学基金（22274045）,神经退行性疾病中核酸-蛋白复合体相分离的化学测量学方法研究。在研。
2.国家自然科学基金（21874042），癌细胞外泌体的生物分析新方法与临床样品检测研究。
3.国家自然科学基金（21475043），Ⅳ族元素量子点的电化学制备及其在生物分析中的应用。
4.国家自然科学基金（21275051），基于上转换纳米编码探针的多种肿瘤标志物同时检测技术。
5..国家自然科学基金（20975037），基于功能化蛋白核壳纳米编码信标的核酸适体阵列传感技术研究。
6.国家自然科学基金（20675030），基于纳米颗粒编码的DNA单碱基突变检测技术研究。
7.国家自然科学基金协作项目（21327806），生物荧光探针的合成与表征。
代表性论文（部分）
1.Dan Liu，Kangkang Weng，Shaoyong Lu，Fu Li，Hannikezi Abudukeremu，Lipeng Zhang，Yuchen Yang，Junyang Hou，Hengwei Qiu，Zhong Fu，Xiyu Luo，Lian Duan，Youyu Zhang*，Hao Zhang*，Jinghong Li, Direct optical patterning of perovskite nanocrystals with ligand cross-linkers. Science Advances,2022,8,eabm8433.
2.Feng Chen，Qiujun Lu，Linna Huang，Biwu Liu，Meiling Liu，Youyu Zhang*，Juewen Liu*, DNA triplex and quadruplex assembled nanosensorsfor correlating K+and pH in lysosomes. Angewandte Chemie International Edition, 2021, 60, 5453-5458.
3.Yuquan Xiao,Boru Peng, Xiaohua Zhu*, Ying Long, Feng Liu, Meiling Liu, Haitao Li,Youyu Zhang*, Shouzhuo Yao,Machine learning-assisted multichannel nanosensor based on core-shell carbon dot/gold nanoparticle composites for rapid and precise intraoperative oral cancer malignancy diagnosis,Science China-Chemistry, 2025, 68,5273-5283.
4.Zile Zhou, Cong Fang, Juan Xie, Youyu Zhang*, Haitao Li,Elucidation of therelationship betweenhydrogenperoxide andpyroptosis by asuperior near-infraredfluorescentprobe, Analytical Chemistry, 2026, 98,6021-6033.
5.Biao Gu, Zhao, Jingjun Zhao, Siping TangHaitao Li, Ruiqing Long, Lijia Wang, Yacong Liao, Yaqian Li*, Wen Chen*,YouyuZhang*, Membrane-targetabledual-responsivepluorescentprobe forsimultaneousdetection ofpolarity andhypochlorite andttsapplication inapoptosis andcancermodels,Analytical Chemistry, 2026, 98,6021-6033.
6.Shuhang Yin,; Feng Chen, Boru Peng, Yongyan Shi, Qiujun Lu, Xiaohua Zhu*, Haitao Li,Youyu Zhang*，Visualization ofcancercell-derivedexosome-inducedfibroblastphenotypictransformation,AnalyticalChemistry, 2025,97,7098-7106,
7.Shuhang Yin,,Binbin Li,Boru Peng,Yongyan Shi,Feng Chen,Qiujun Lu,Xiaohua Zhu*,Meiling LiuHaitao Li,Youyu Zhang*,DNAretrahedralsensors forvisualizing miR-21-mediatedangiogenesis, Analytical Chemistry, 2025, 97,19249-19257.
8.Shuhang Yin, Yang Zhao, Feng Chen, Zijie Zhong, Qiujun Lu, Haitao Li,Youyu Zhang*,DNAsensor-basedstrategy tovisualize the TRPM7 mRNA-Mg2+signalingpathway incancercells,Analytical Chemistry，2023, 95,18107-18113.
9.Jianhui Deng，Qiujun Lu，Yuxin Hou，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Nanosensor composed of nitrogen-doped carbon dots and gold nanoparticles for highly selective detection of cysteine with multiple signals.Analytical Chemistry, 2015 87,(4),2195-2203.
10.Xiaojiao Chen，Yangzhong Wang，Youyu Zhang*，Zhuhai Chen，Yang Liu*，Zhaolong Li，Jinghong Li, Sensitive electrochemical aptamer viosensor for dynamic cell surface N-Glycan evaluation featuring multivalent recognition and signal amplification on a dendrimer-grapheneelectrodeinterface.Analytical Chemistry,2014,86,4278-4286.
11.Yinhui Yi，Gangbing Zhu，Chang Liu，Yan Huang，Youyu Zhang*，Haitao Li，Jiangna Zhao，Shouzhuo Yao, A label-free silicon quantum dots-based photoluminescence sensor for ultrasensitive detection of pesticides. Analytical Chemistry,2013 ,85,,11464-11470.
12.Youyu Zhang，Zhiwen Tang，Jun Wang，Hong Wu，Aihui Maham，Yuehe Lin*, Hairpin DNA switch for ultrasensitive spectrophotometric detection of DNA hybridization based on gold nanoparticles and enzyme signal amplification.Analytical Chemistry, 2010, 82, 6440-6446.
13.Qiongqiong Wu，Hongyu Chen，Aijin Fang，Xinyang Wu，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Universalmultifunctionalnanoplatformbased ontarget-induced insitupromoting Auseedsgrowth toquenchfluorescence ofupconversionnanoparticles. Acs Sensors,2017 2,(12),1805-1813.
14.Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*,One-step electrochemical synthesis of ultrathin graphitic carbon nitride nanosheets and their application to the detection of uric acid. Chemical Communications, 2015, 51, 12251-12253.
15.Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Hydroxyl-rich C-dots synthesized by a one-pot method and their application in the preparation of noble metal nanoparticles. Chemical Communications, 2015, 51, 7164-7167.
16.Qiong Chen，Meiling Liu，Jiangna Zhao，Xue Peng，Xiaojiao Chen，Naxiu Mi，Bangda Yin，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose. Chemical Communications, 2014,50,6771-6774.
17.Mingjie Wei，Peng Yin，Youming Shen，Lingli Zhang，Jianhui Deng，Shanyan Xue，Haitao Li，Bin Guo，Youyu Zhang*，Shouzhuo Yao, A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells. Chemical Communications, 2013, 49,4640-4642.
18.Yinhui Yi，Jianhui Deng，Youyu Zhang*，Haitao Li，Shouzhuo Yao, Label-free Si quantum dots as photoluminescence probes for glucose detection.Chemical Communications, 2013, 49,612-614.
19.Dan Liu，Gong Zhang，Qinghua Ji，Youyu Zhang*，Jinghong Li*, Synergistic electrocatalytic nitrogen reduction enabled by confinement of nanosized Au particles onto a two-dimensional Ti3C2substrate. Acs Applied Materials & Interfaces, 2019, 11, 25758-25765.
20.Mingxia Li，Qiujun Lu，Meiling Liu，Peng Yin，Cuiyan Wu，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Photoinduced charge separation via the double-electron transfer mechanism in nitrogen vacancies g-C3N5/BiOBr for the photoelectrochemical nitrogen reduction. Acs Applied Materials & Interfaces,2020,12,38266-38274.
联系方式
Email：zhangyy@hunnu.edu.cn,zhangyy0101@126.com
Tel:+86-13787296080
（更新于2026年5月）
