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张友玉，博士，二级教授，博士生导师。主要从事化学生物学及纳米分析化学等领域的研究。主持国家自然科学基金面上项目5项，国家基金重点项目协作项目1项，省部级重点及一般项目10余项。以第一作者和通讯作者在Sci. Adv.,Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun.等国际著名刊物上发表高水平研究论文200余篇，获国家授权发明专利7项。获湖南省自然科学奖二等奖1项，湖南省科学技术进步奖二等奖1项，中国分析测试学会科学技术奖（CAIA奖）二等奖1项。获2018年湖南师范大学芙蓉百岗明星称号。 主持课题（部分）： 1.国家自然科学基金（21874042）,癌细胞外泌体的生物分析新方法与临床样品检测研究。在研。 2.国家自然科学基金（21475043）,Ⅳ族元素量子点的电化学制备及其在生物分析中的应用。 3.国家自然科学基金（21275051）,基于上转换纳米编码探针的多种肿瘤标志物同时检测技术。 4.国家自然科学基金（20975037）,基于功能化蛋白核壳纳米编码信标的核酸适体阵列传感技术研究。 5.国家自然科学基金（20675030）,基于纳米颗粒编码的DNA单碱基突变检测技术研究。 6.国家自然科学基金协作项目（21327806），生物荧光探针的合成与表征。 代表性论文（部分）： 1.Dan Liu，Kangkang Weng，Shaoyong Lu，Fu Li，Hannikezi Abudukeremu，Lipeng Zhang，Yuchen Yang，Junyang Hou，Hengwei Qiu，Zhong Fu，Xiyu Luo，Lian Duan，Youyu Zhang*，Hao Zhang*，Jinghong Li,Direct optical patterning of perovskite nanocrystals with ligand cross-linkers.Science Advances,2022 8,(11),eabm8433. 2.Feng Chen，Qiujun Lu，Linna Huang，Biwu Liu，Meiling Liu，Youyu Zhang*，Juewen Liu*,DNA Triplex and Quadruplex Assembled Nanosensorsfor Correlating K+and pH in Lysosomes.Angewandte Chemie International Edition,2021 60,5453-5458. 3.Jianhui Deng，Qiujun Lu，Yuxin Hou，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles for Highly Selective Detection of Cysteine with Multiple Signals.Analytical Chemistry,2015 87,(4),2195-2203. 4.Xiaojiao Chen，Yangzhong Wang，Youyu Zhang*，Zhuhai Chen，Yang Liu*，Zhaolong Li，Jinghong Li,Sensitive Electrochemical Aptamer Biosensor for Dynamic Cell Surface N-Glycan Evaluation Featuring Multivalent Recognition and Signal Amplification on a Dendrimer-Graphene Electrode Interface.Analytical Chemistry,2014 86,(9),4278-4286. 5.Yinhui Yi，Gangbing Zhu，Chang Liu，Yan Huang，Youyu Zhang*，Haitao Li，Jiangna Zhao，Shouzhuo Yao,A Label-Free Silicon Quantum Dots-Based Photoluminescence Sensor for Ultrasensitive Detection of Pesticides.Analytical Chemistry,2013 85,(23),11464-11470. 6.Youyu Zhang，Zhiwen Tang，Jun Wang，Hong Wu，Aihui Maham，Yuehe Lin*,Hairpin DNA Switch for Ultrasensitive Spectrophotometric Detection of DNA Hybridization Based on Gold Nanoparticles and Enzyme Signal Amplification.Analytical Chemistry,2010 82,(15),6440-6446. 7.Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*,One-step electrochemical synthesis of ultrathin graphitic carbon nitride nanosheets and their application to the detection of uric acid.Chemical Communications,2015 51,(61),12251-12253. 8.Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Hydroxyl-rich C-dots synthesized by a one-pot method and their application in the preparation of noble metal nanoparticles.Chemical Communications,2015 51,(33),7164-7167. 9.Qiong Chen，Meiling Liu，Jiangna Zhao，Xue Peng，Xiaojiao Chen，Naxiu Mi，Bangda Yin，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose.Chemical Communications,2014 50,(51),6771-6774. 10.Mingjie Wei，Peng Yin，Youming Shen，Lingli Zhang，Jianhui Deng，Shanyan Xue，Haitao Li，Bin Guo，Youyu Zhang*，Shouzhuo Yao,A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells.Chemical Communications,2013 49,(41),4640-4642. 11.Yinhui Yi，Jianhui Deng，Youyu Zhang*，Haitao Li，Shouzhuo Yao,Label-free Si quantum dots as photoluminescence probes for glucose detection.Chemical Communications,2013 49,(6),612-614. 12.Jianhui Deng，Qiujun Lu，Naxiu Mi，Haitao Li，Meiling Liu，Mancai Xu，Liang Tan，Qingji Xie，Youyu Zhang*，Shouzhuo Yao,Electrochemical Synthesis of Carbon Nanodots Directly from Alcohols.Chemistry-a European Journal,2014 20,(17),4993-4999. 13.Youyu Zhang，Zhiwen Tang，Jun Wang，Hong Wu，Chiann-Tso Lin，Yuehe Lin*,Apoferritin nanoparticle: a novel and biocompatible carrier for enzyme immobilization with enhanced activity and stability.Journal Of Materials Chemistry,2011 21,(43),17468-17475. 14.Zile Zhou，Shengyou Chen，Yinghui Huang，Biao Gu，Jiaqi Li，Cuiyan Wu，Peng Yin，Youyu Zhang*，Haitao Li*,Simultaneous visualization and quantification of copper (II) ions in Alzheimer's disease by a near-infrared fluorescence probe.Biosensors & Bioelectronics,2022 198,113858. 15.Mingxia Li，Haiyan Wang，Xiaoxia Wang，Qiujun Lu，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Ti3C2/Cu2O heterostructure based signal-off photoelectrochemical sensor for high sensitivity detection of glucose.Biosensors & Bioelectronics,2019 142. 16.Qiujun Lu，Haiyan Wang，Yalan Liu，Yuxin Hou，Haitao Li，Youyu Zhang*,Graphitic carbon nitride nanodots: As reductant for the synthesis of silver nanoparticles and its biothiols biosensing application.Biosensors & Bioelectronics,2017 89411-416. 17.Aijin Fang，Hongyu Chen，Haitao Li，Meiling Liu*，Youyu Zhang*，Shouzhuo Yao,Glutathione regulation-based dual-functional upconversion sensing-platform for acetylcholinesterase activity and cadmium ions.Biosensors & Bioelectronics,2017 87545-551. 18.Aijin Fang，Qiongqiong Wu，Qiujun Lu，Hongyu Chen，Haitao Li，Meiling Liu*，Youyu Zhang*，Shouzhuo Yao,Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.Biosensors & Bioelectronics,2016 86664-670. 19.Qian Long，Aijin Fang，Yanqing Wen，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Rapid and highly-sensitive uric acid sensing based on enzymatic catalysis-induced upconversion inner filter effect.Biosensors & Bioelectronics,2016 86109-114. 20.Qiongqiong Wu，Aijin Fang，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Enzymatic-induced upconversion photoinduced electron transfer for sensing tyrosine in human serum.Biosensors & Bioelectronics,2016 77957-962. 21.Qian Long，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Upconversion nanoparticle-based fluorescence resonance energy transfer assay for organophosphorus pesticides.Biosensors & Bioelectronics,2015 68168-174. 22.Meiling Liu，Jianhui Deng，Qiong Chen，Yan Huang，Linping Wang，Yan Zhao，Youyu Zhang*，Haitao Li，Shouzhuo Yao*,Sensitive detection of rutin with novel ferrocene benzyne derivative modified electrodes.Biosensors & Bioelectronics,2013 41275-281. 23.Jie Zhao，Youyu Zhang*，Haitao Li，Yanqing Wen，Xiaoyu Fan，Fanbo Lin，Liang Tan，Shouzhuo Yao,Ultrasensitive electrochemical aptasensor for thrombin based on the amplification of aptamer-AuNPs-HRP conjugates.Biosensors & Bioelectronics,2011 26,(5),2297-2303. 24.Min Ye，Youyu Zhang*，Haitao Li，Yuqin Zhang，Ping Tan，Hao Tang，Shouzhuo Yao,A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.Biosensors & Bioelectronics,2009 24,(8),2339-2345. 25.Mingxia Li，Qiujun Lu，Meiling Liu，Peng Yin，Cuiyan Wu，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Photoinduced Charge Separation via the Double-Electron Transfer Mechanism in Nitrogen Vacancies g-C3N5/BiOBr for the Photoelectrochemical Nitrogen Reduction.Acs Applied Materials & Interfaces,2020 12,(34),38266-38274. 26.Dan Liu，Gong Zhang，Qinghua Ji，Youyu Zhang*，Jinghong Li*,Synergistic Electrocatalytic Nitrogen Reduction Enabled by Confinement of Nanosized Au Particles onto a Two-Dimensional Ti3C2Substrate.Acs Applied Materials & Interfaces,2019 11,(29),25758-25765. 27.Na Huang，Si Zhang，Liuqing Yang，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Multifunctional Electrochemical Platforms Based on the Michael Addition/Schiff Base Reaction of Polydopamine Modified Reduced Graphene Oxide: Construction and Application.Acs Applied Materials & Interfaces,2015 7,(32),17935-17946. 28.Qiongqiong Wu，Hongyu Chen，Aijin Fang，Xinyang Wu，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Universal Multifunctional Nanoplatform Based on Target-Induced in Situ Promoting Au Seeds Growth to Quench Fluorescence of Upconversion Nanoparticles.Acs Sensors,2017 2,(12),1805-1813. 29.Qujun Lu，Hu Dong，Jiali Hu，Linna Huang，Youyu Zhang*，Mingxia Li，Meiling Liu，Yaqian Li，Cuiyan Wu*，Haitao Li,Insight into the Effect of Ligands on the Optical Properties of Germanium Quantum Dots and Their Applications in Persistent Cell Imaging.Langmuir,2020 36,(41),12375-12382. 30.Jiali Hu，Qiujun Lu，Cuiyan Wu，Meiling Liu，Haitao Li，Youyu Zhang*，Shouzhuo Yao,Synthesis of Fluorescent and Water-Dispersed Germanium Nanoparticles and Their Cellular Imaging Applications.Langmuir,2018 34,(30),8932-8938. 联系方式： Email：zhangyy@hunnu.edu.cn,zhangyy0101@126.com Tel:+86-13787296080 （更新于2022年3月） |
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