基本信息：
邹振，男，博士，副教授，湖南省优青，“世承计划”青年优秀人才。
邮箱: 474779970@qq.com
个人简介：
湖南师范大学化学化工学院国家杰青、教育部长江学者杨荣华教授团队成员。主要从事分子水平和纳米尺度上的分子生物医学研究。聚焦于核酸荧光传感与分子识别的关键科学问题，系统开展基于核酸的生化传感新原理与新方法的基础应用研究，构建疾病分子诊断与生物调控、环境与食品安全分析的新方法。目前主持承担国家自然科学基金面上项目和青年项目、湖南省自然科学基金优秀青年项目、湖南省教育厅重点项目和优秀青年项目、长沙市自然科学基金等多项研究课题。已在Journal of the American Chemical Society、Angewandte Chemie International Edition、Biomaterials、CCS Chemistry、Coordination Chemistry Reviews、Analytical Chemistry等国际权威期刊发表论文30余篇，申请发明专利9项，参编专著1部。湖南省研究生创新项目指导老师（3项）。与中南大学湘雅医院、湖南省肿瘤医院、湖南省人民医院等保持良好合作关系，针对临床问题展开科学研究，努力在分子诊断、疾病治疗等相关领域推进成果转化，产生效益。
主讲课程：
1. 本科生课程：《分析化学》、《分析化学实验》、《仪器分析实验》《化学信息学》
2. 研究生课程：《科研方法与学术规范》、《纳米材料化学》
近年主持的科研项目：
1. 国家自然科学基金面上项目，22474037，基于三链核酸的基因座原位成像与空间解析，2025/01-2028/12, 50万，主持
2. 国家自然科学基金重点项目, 22334005, 基于生物正交化学的细胞功能行为精准监测，2024/01-2028/12, 230万，参与
3. 湖南省自然科学基金优秀青年基金项目，2019JJ50653，高生物亲和性纳米诊疗体系的构建与应用，2022/01-2024/12，20万，主持
4. 国家自然科学基金青年项目, 21705010，三链DNA编码的纳米孔技术用于肿瘤标志物的同步分析，2018/01-2020/12，25万，主持
5.湖南省教育厅重点项目, 23A0059, 线粒体干扰型纳米中药用于肺癌原发灶和转移灶靶向抑制, 2023/09-2025/09, 6万元, 在研, 主持
6. 湖南省教育厅优秀青年项目，20B032，三链核酸介导的双microRNA 浓缩及其肿瘤协同治疗的研究，2020/09-2022/09，7万元，主持
7. 湖南省自然科学基金青年基金项目，2019JJ50653，三链核酸框架纳米结构介导的microRNA靶向递送及肿瘤成像，2019/01-2021/12，5万，主持
8. 国家自然科学基金重大研究计划培育项目, 91853104，p66Shc蛋白磷酸化调控肾小管上皮细胞凋亡通路的原位荧光分析，2019/01-2021/12，60万，参与
代表性论文与专利：
(1) Ke Quan, Xiaoyuan Li, Jiaqi Deng, Weiju Chen, Zhen Zou*, Kun Chen, Linlin Wu, Juewen Liu, Zhihe Qing*. Pt-decorated gold nanoflares for high-fidelity phototheranostics: reducing side-effects and enhancing cytotoxicity toward target cells. Angewandte Chemie International Edition, 2024, 63: e202402881
(2) Zhen Zou, Libei He, Xiangxi Deng, Huangxiang Wang, Ziyun Huang, Qian Xue, Zhihe Qing*, Yanli Lei, Ronghua Yang*, Juewen Liu. Zn2+-coordination-driven RNA assembly with retained integrity and biological functions. Angewandte Chemie International Edition, 2021, 60: 22970-22976.
(3) Yue Su, Yiting Liu, Yaling Zhong, Shimeng Ma, Qinqin Ouyang, Xiang Chen, Yinfeng Li, Erhu Xiong, Zhen Zou*, Juewen Liu. Coordination-driven self-assembly of biomolecules and metal ions: Advances in methodology and applications. Coordination Chemistry Reviews, 2025, DOI: 10.1016/j.ccr.2024.216403.
(4) Zhen Zou*, Songlan Pan, Qian Xue, Ting Chen, Ziyun Huang, Bei Qing, Pengfei Liu, Conghui Zhao, Yunlin Sun, Erhu Xiong*, Ronghua Yang. Artificial nucleic acid tractor-directed simultaneous depletion of oncogenic membrane proteins without hijacking proteolysis-specific actuator. CCS Chemistry, 2024, 6: 439-449.
(5) Rui Wang, Lei Zhou, Yueyan Yang, Furong Zhao, Xianbao Sun, Xiaoyang Liu, Zhen Zou, Gaolin Liang*. Spatially quantitative imaging of enzyme activity in a living cell. Journal of the American Chemical Society, 2024, 146: 34870−34877.
(6) Ting Chen, Pengfei Liu, Huanxiang Wang, Yue Su, Sheng Li, Shimeng Ma, Xuan Xu, Jie Wen, Zhen Zou*. Dumbbell-type triplex molecular switch-based logic molecular assays of SARS-CoV-2. Sensors and Actuators B: Chemical, 2022, 371: 132579.
(7) Lihua Zhang, Minzhi Ouyang, Yufei Zhang, Leiyi Zhang, Ziyun Huang, Libei He, Yanli Lei, Zhen Zou*, Feng Feng*, Ronghua Yang*. The fluorescence imaging and precise suppression of bacterial infections in chronic wounds by porphyrin-based metal-organic framework nanorods. Journal of Materials Chemistry B, 2021, 9: 8048-8055.
(8) Zhen Zou, Xiaodou Liao, Le Yang, Ziyun Huang, Hua Yang, Qi Yan, Yufei Zhang, Zhihe Qing, Lihua Zhang, Feng Feng, Ronghua Yang*, Human serum albumin-occupying-based fluorescence turn-on analysis of antiepileptic drug tiagabine hydrochloride. Analytical Chemistry, 2020, 92(5): 3555-3562.
(9) Zhen Zou, Ziling Luo, Xuan Xu, Sheng Yang, Zhihe Qing, Juewen Liu, Ronghua Yang*, Photoactivatable fluorescent probes for spatiotemporal-controlled biosensing and imaging. TrAC Trends in Analytical Chemistry, 2020, 125: 115811.
(10) Le Yang, Jin Zheng, Zhen Zou*, Haiyan Cai, Peng Qi, Zhihe Qing, Qi Yan, Liping Qiu, Weihong Tan, Ronghua Yang*, Human serum albumin as an intrinsic signal amplification amplifier for ultrasensitive assays of the prostate-specific antigen in human plasma. Chemical Communications, 2020, 56: 1843-1846.
(11) Zhen Zou, Hua Yang, Qi Yan, Peng Qi, Zhihe Qing, Jing Zheng, Xuan Xu, Lihua Zhang, Feng Feng, Ronghua Yang*, Synchronous screening of multiplexed biomarkers of Alzheimer's disease by a length-encoded aerolysin nanopore-integrated triple-helix molecular switch. Chemical Communications, 2019, 55: 6433-6436.
(12) Zhen Zou, Qi Yan, Sixin Ai, Peng Qi, Hua Yang, Yufei Zhang, Zhihe Qing, Lihua Zhang, Feng Feng, Ronghua Yang*, Real-time visualizing mitophagy-specific viscosity dynamic by mitochondria-anchored molecular rotor. Analytical Chemistry, 2019, 91: 8574−8581.
(13) Zhen Zou, Peng Qi, Zhihe Qing, Jing Zheng, Sheng Yang, Weiju Chen, Ronghua Yang*, Technologies for analysis of circulating tumour DNA: Progress and promise. Trends in Analytical Chemistry, 2017, 97: 36-49.
(14) Zhen Zou, Dinggeng He, Linli Cai, Xiaoxiao He*, Kemin Wang*, Xue Yang, Liling Li, Siqi Li, Xiaoya Su, Alizarin complexone functionalized mesoporous silica nanoparticles: a smart system integrating glucose-responsive double-drugs release and real-time monitoring capabilities. ACS Applied Materials & Interfaces, 2016, 8: 8358-8366.
(15) Zhen Zou, Xiaoxiao He*, Dinggeng He, Kemin Wang*, Zhihe Qing, Xue Yang, Li Wen, Jun Xiong, Liling Li, Linli Cai. Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and release. Biomaterials, 2015, 58: 35-45.
(1) 邹振; 廖小豆; 杨荣华; 闫奇; 杨华 ; 抗癫痫药物---盐酸噻加宾(TGB)的荧光检测方法, 2022-04-22, 中国, CN201910383680.2
(2) 邹振; 贺丽蓓; 杨荣华; 齐鹏; 杨华; 罗梓凌 ; 一种血清中前列腺特异性抗原的分析方法, 2022-03-29, 中国, CN201910389359.5
(3) 邹振; 贺丽蓓; 赵聪慧; 王焕翔; 黄梓芸; 孙芸琳 ; 一种RNA的封装方法, 2023-01-24, 中国, CN202110318427.6
